AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMoreFor the last 7 months, Trenton Lewis had been diligently waking up in the pre-dawn morning so he could make the 5.5-mile hike to work in time for his 4AM shift. Then, after a long day’s work, he would walk the same distance all the way back home again.Despite the 21-year-old father never telling any of his co-workers at the UPS facility in Little Rock, Arkansas, the workforce eventually found out about his exhausting commute.But instead of allowing the dedicated dad to continue hiking to and from work every day, they all pitched in enough money to buy him a new car.According to WTVR, Lewis’s coworker Kenneth Bryant said: “Everybody who I talked to said yes! The hardest part was reminding them to bring cash.WATCH: Bus Driver’s “Ecstatic” Reaction to Students Surprising Him With Super Bowl Tickets“I told the seller what I was doing and who it was for and he said he was willing to work with me on a price,” he added.Bryant was eventually able to buy a 2006 Saturn Ion for a mere $2,000. The workforce then lured Lewis to the parking lot for a brief “union meeting” last week.When Lewis joined all of his co-workers in the lot, however, they handed him the keys to the Saturn.RELATED: Student Wakes From Nap to Find That Stranger Had Overheard Her Financial Difficulties and Left a GiftThough Lewis is reportedly described as “stoic”, he could not contain his emotions over the gift.“For a young person to decide in their mind ‘if I don’t have a ride, if I can’t get a ride then I’ll walk,’” said Bryant, “if a guy can do that, we can pitch in to help.”Furthermore, Lewis says that the first thing he did in his new car was pick up his 14-month-old daughter so they could get a bite to eat.(WATCH the video below)Click To Share The Sweet Surprise With Your Friends AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMore
AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMoreBreast cancer could be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumor cells.Cancer cells produce proteins called antigens that trigger the body to make antibodies against them: autoantibodies. According to new research presented at the 2019 NCRI Cancer Conference earlier this week by researchers at the University of Nottingham (UK), these tumor-associated antigens (TAAs) are good indicators of cancer, and now they have developed panels of TAAs that are known already to be associated with breast cancer to detect whether or not there are autoantibodies against them in blood samples taken from patients.In a pilot study, the researchers took blood samples from 90 breast cancer patients at the time they were diagnosed with breast cancer and matched them with samples taken from 90 patients without breast cancer (the control group). They used screening technology (protein microarray) that allowed them to screen the blood samples rapidly for the presence of autoantibodies against 40 TAAs associated with breast cancer, and also 27 TAAs that were not known to be linked with the disease.RELATED: Husband-Wife Duo Has Developed ‘Gene and Cell Therapy’ Cancer Vaccine Now Being Tested on Patients“The results of our study showed that breast cancer does induce autoantibodies against panels of specific tumor-associated antigens,” said Daniyah Alfattani, a PhD student in the group who presented the research at the NCRI Conference. “We were able to detect cancer with reasonable accuracy by identifying these autoantibodies in the blood.”The researchers identified three panels of TAAs against which to test for autoantibodies. The accuracy of the test improved in the panels that contained more TAAs. The panel of five TAAs correctly detected breast cancer in 29% of the samples from the cancer patients and correctly identified 84% of the control samples as being cancer-free. The panel of seven TAAs correctly identified cancer in 35% of cancer samples and no cancer in 79% of control samples. The panel of nine antigens correctly identified cancer in 37% of cancer samples and no cancer in 79% of the controls.“We need to develop and further validate this test,” said Alfattani. “However, these results are encouraging and indicate that it’s possible to detect a signal for early breast cancer. Once we have improved the accuracy of the test, then it opens the possibility of using a simple blood test to improve early detection of the disease.”CHECK OUT: Indonesian Teens Use Native Tree Species to Cure Rats of Breast CancerThe researchers are now testing samples from 800 patients against a panel of nine TAAs, and they expect the accuracy of the test to improve with these larger numbers.“A blood test for early breast cancer detection would be cost effective, which would be of particular value in low and middle income countries. It would also be an easier screening method to implement compared to current methods, such as mammography,” said Alfattani.The researchers estimate that, with a fully-funded development program, the test might become available in the clinic in about four to five years.RELATED: Apples, Tea, and Moderation—The 3 Ingredients for a Long LifeA similar test for lung cancer is currently being tested in a randomized controlled trial in Scotland, involving 12,000 people at high risk of developing lung cancer because they smoke. They have been randomized to have (or not) an autoantibody blood test called ELISA (Early CDT-Lung). Participants who test positive for the autoantibodies are then followed up with a CT scan every two years in order to detect lung cancer in its early stages when it is easier to treat.The CEAC group is also working on similar tests for pancreatic, colorectal and liver cancers. Solid tumors like these, as well as lung and breast cancer, represent around 70% of all cancers.MORE: Broccoli Isn’t Just Good For You; Scientists Find It Holds Molecule That Could Be the ‘Achilles’s Heel’ of Cancer“A blood test capable of detecting any of these cancers at an early stage is the over-riding objective of our work,” concluded Alfattani.“Early diagnosis using simple, non-invasive ways of detecting the first signs of cancer is a key strategic priority for NCRI and something we’d all like to see working in practice,” said NCRI CEO Dr. Iain Frame. “The results from this pilot study for a blood test to detect early breast cancer are promising and build on this research group’s expertise in other cancers, such as lung cancer. It’s obviously early days but we look forward to seeing the results from the larger group of patients that are now being investigated.”Reprinted from the NCRITreat Your News Feed To Some Positivity By Sharing The Good News With Your Friends On Social Media – File photo by Aldenchadwick, CCAddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMore
The latest cranks from Rotor are the 2INpower dual sided power meter crankset. It uses the spindle-mounted strain gauge of the original, single-sided INpower cranks with a second strain gauge inside the right crank arm: The Dimension Data pro cycling team had two sets of Cervelo S5 bikes on hand. The majority were equipped with Shimano Dura-Ace Di2 handling the shifting, but a few were sitting atop team cars with the new Rotor UNO hydraulic shifting group. Starting with the former, the spec mostly carries over from what we saw at the Tour de France last year when they were called MTN-Qhubeka. That means ENVE wheels, bar and stem, Continental tires and Rotor cranks.This time around, we took a closer look at the CeramicSpeed upgrades and photo’d the all-hydraulic backup bikes… After giving the crankset a back spin, we inquired about the setup because it moves effortlessly. Even brand new bikes sitting on the showroom floor don’t spin this freely. The reason? They’ve replaced every moving part except the pedal’s bearings with CeramicSpeed components. That includes the headset, hub bearings, bottom bracket and derailleur pulley wheels. They also use CeramicSpeed’s lube oil on the chain, which is outside the intended use parameters, but when your bikes are cleaned and maintained daily, you can get away with stuff like that.Interestingly, they’re not running the massively oversized CS pulley wheels introduced last fall. We didn’t get a chance to ask why, but it’s likely because a sponsor like Shimano wouldn’t take too kindly to such modifications (though it doesn’t seem to stop Cannondale) This bike shows what a full hydraulic component group will look like (it’s still chain driven, of course).The lever body contains the master cylinder for the brakes, but none is required for the shifting system because it’s completely closed. Check our tech breakdown of the entire group for more the deep dive. These hoods look big, but Rotor’s said they could probably offer a smaller size option for those with smaller hands.We’ll be riding UNO in early April with the engineers at Rotor, stay tuned for a first ride report.If you’ve seen Acros’ hydraulic shifters and derailleurs, you’ll notice UNO uses just one single hose rather than two. That’s possible thanks to a clever ratcheting system that either catches and holds, or releases, depending on how far it’s pushed.These rather large connectors in the brake lines allow bleed-free disconnects between the levers and the Magura RT8 hydraulic rim brake calipers. These don’t look quite like the stock offerings from Magura.They have an external dial sticking out and up from the center mounting bolt, which looks like it could simply be a pad contact adjustment / release mechanism to speed wheel changes.